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Kaiser Permanente Dramatically Diminishes Patient’s Tremors

Richard Williams’ tremors limited his life. Then a complex surgery put him back in control. Pictured, Williams with Patrick Pezeshkian, MD, and Rima Ash, MD.

For Richard Williams, the past 20 years have not been easy.

He was diagnosed with Parkinson’s disease and essential tremor in 2004. Through the years, his symptoms grew progressively worse.

“Over time, my tremors really impacted my life,” said Williams, 70. “I couldn’t eat soup because it was too hard to control the spoon. It was challenging to insert a credit card into the self-service slot at gas stations. Little things became very difficult.”

Mr. Williams speaks in the past tense because those days are behind him, thanks to Kaiser Permanente.

The St. Jude Device

Williams, a retiree who lives in Sonoma, receives his care from neurologist Rima Ash, MD, at Kaiser Permanente San Francisco. Last April she came to Williams with an idea.

“I thought he was a perfect candidate for a surgery called deep brain stimulation, or DBS,” Dr. Ash explained. “Mr. Williams is in good health, tech-savvy, and he really wanted to go beyond medications to treat his tremors.”

With DBS, a surgeon implants wire leads deep in the right and left sides of the brain to emit pulses of energy. These block the brain activity causing the tremors. Next a generator much like a pacemaker is implanted below the clavicle, which is later programmed to deliver high-frequency stimulation to the leads until the target area is responding, thus improving the patient’s tremors.

Dr. Ash explained that the St. Jude device is special for 2 reasons: It is the world’s first wireless device, and it has multiple segmented contacts, allowing for more precise programming, meaning that it would be that much more accurate in diminishing Williams’ tremors.

If approved for the surgery, he would be Kaiser Permanente’s first St. Jude device patient.

“I immediately said, ‘Let’s go for it,’” Williams said.

A Perfect Circle

The ensuring months showed Williams the breadth and depth of care at Kaiser Permanente, tapping into the expertise of the neurologists, bioengineers, nurse practitioners, neuropsychologists, and many more.

Dr. Ash would program the device, but first Patrick Pezeshkian, MD, a neurosurgeon at Kaiser Permanente Redwood City and one of several specializing in DBS at Kaiser Permanente in Northern California, would perform 2 surgeries.

Williams first underwent numerous physical and cognitive tests. After passing those, his case was reviewed and surgery approved by a large board of clinicians.

On Jan. 3 and Jan. 17, Williams underwent 2 separate 6-hour surgeries. He was awake for almost all of it, with physician assistant Diana Bruce coaching him, until the final hour when the generator was placed in his chest.

Mr. Williams provides wineries with glass cutting boards he designs through “The Third Adventure.” Recently he visited a winery where he unpacked his cutting boards, traded business cards, and signed his signature — simple tasks most take for granted but that he treasures.
Mr. Williams provides wineries with glass cutting boards he designs through “The Third Adventure.” Recently he visited a winery where he unpacked his cutting boards, traded business cards, and signed his signature — simple tasks most take for granted but that he treasures.

“During the surgery, Dr. Pezeshkian had me draw circles and lines, which were just terrible,” Williams said. “But when he first tested out the working leads during surgery, I could draw perfectly. All I could say was, ‘Wow.’ I almost cried.”

Iced Tea and iPods

Williams recovered well, and began the series of programming sessions with Dr. Ash in San Francisco. Using her iPad, she meticulously tests each of the leads, their different combinations and strengths, in her pursuit of the best setting.

“In the first session, we found a sort of medium spot for just a baseline,” Williams said. “Right afterward I went to lunch with my wife and youngest daughter and was suddenly able to hold a glass of iced tea with one hand, steadily. I can’t remember the last time I could do that!”

Since then, Dr. Ash has taught Williams how to use an iPod to control the leads himself. He turns it on when he wakes and off again at bedtime.

“I can’t say enough about the professionalism and skill of my doctors and their ability to do incredible things,” Williams said. “But really I had an amazing support system from everyone at Kaiser Permanente. I could feel their concern, and that everyone was right by my side throughout.”


physiciansRedwood CitySan Franciscospecialty care

This Post Has 5 Comments

  1. Wow…It’s like the pacemaker for the brain. Happy to hear that there’s hope for people who suffer from Parkinson’s.

  2. Impressive! My father-in-law had to deal with his tremors for 28 years. Unfortunately, he died of the complications of this awful disease. I know he would have tried this….

  3. Outstanding! What a joint success for our KP physicians and staff. This is
    such a remarkable outcome for Mr. Williams. How wonderful that his quality of life
    has been so positively impacted.

  4. This is great! I’m wondering if you’ve seen the study where they are finding that a specific type of cycling (meaning there has to be a certain heart rate and cycling done for a certain amount of time) seems to be helping patients with Parkinson’s? This is just a trial, but the results are astounding. I love when something works (such as surgery) and it helps the patient.

    1. I am a member of Kaiser, with Parkinson’s. You are probably referring to The Theracycle! It began a lot of research about how exercise on a “forced intensity” stationary bike can help people with PD so much! I own one — it helps me so much!

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